24-Hour Pharmacies Near Me in NYC

Where to Find a Round-the-Clock Drugstore in Your Neighborhood

24-Hour Pharmacies Near Me in NYC
••• Photo credit: Spencer Platt / Getty Images

Whether you need cough medicine for your little one or an emergency prescription refill, sometimes you just can't wait until 9am. These 24-hour Manhattan pharmacies are open around the clock, most with full-time pharmacy services. To make it easier to find the pharmacy near you, we've created separate lists for Downtown, Midtown, and Uptown drugstores.

Downtown (below 23rd St.)

  • Rite-Aid (24-hour pharmacy), 408 Grand St. at Clinton St., 212/529-7115
  • Duane Reade (24-hour store), 769 Broadway at E. 9th St., 646/602-8274
  • Duane Reade(24-hour store), 123 3rd Ave. at 14th St., 212/529-7140
  • Duane Reade(24-hour store), 24 E. 14th St. at University Pl., 212/989-3632
  • Walgreen's (24-hour pharmacy), 145 4th Ave., at 14th St., 212/677-0054
  • Duane Reade (24-hour store), 378 6th Ave. at Waverly Pl., 212/674-5357
  • Duane Reade (24-hour store), 598 Broadway, btwn Houston & Prince sts., 212/343-2567
  • Duane Reade (24-hour store), 180 W. 20th St. at 7th Ave., 212/243-0129
  • CVS (24-hour pharmacy), 342 E. 23rd St. at 2nd Ave. at 2nd Ave., 212/505-1555

Midtown (23rd to 60th sts.)

  • Duane Reade (24-hour store), 401 Park Ave. S. at 28th St., 212/213-9730
  • Duane Reade (24-hour store), 358 5th Ave. at 34th St., 212/279-0208
  • Duane Reade (24-hour store), 460 8th Ave. at 34th St., 212/244-4026
  • Duane Reade (24-hour store), 155 E. 34th St. at 3rd Ave., 212/683-3042
  • Duane Reade (24-hour store), 625 8th Ave. at 40th St., 212/273-0889
  • Duane Reade (24-hour store), 4 Times Square near Broadway, 646/366-8047
  • Duane Reade (24-hour store), 405 Lexington Ave. at 42nd St., 212/808-4743
  • Duane Reade (24-hour store), 852 2nd Ave., btwn 45th & 46th sts., 212/983-1810
  • Duane Reade (24-hour store), 485 Lexington Ave. at 47th St., 212/682-5338
  • Duane Reade (24-hour store), 1633 Broadway at 50th St., 212/586-0374
  • CVS (24-hour pharmacy), 630 Lexington Ave. at 53rd St., 917/369-8688
  • Duane Reade (24-hour store), 900 8th Ave. at 53rd St., 212/582-3463
  • Duane Reade (24-hour store), 866 3rd Ave. at 53rd St., 212/759-9412
  • Duane Reade (24-hour store), 100 W. 57th St. at 6th Ave., 212/956-0464
  • Duane Reade (24-hour pharmacy), 224 W. 57th St. at Broadway, 212/541-9708
  • Duane Reade (24-hour store), 1076 2nd Ave. at 57th St., 212/223-1130
  • Duane Reade (24-hour store), Columbus Circle at 58th St., 212/265-2302
  • CVS (24-hour pharmacy), 400 W. 59th St. at Columbus Ave., 212/245-0617

Uptown (above 60th St.)

  • Duane Reade (24-hour store and express kiosk), 773 Lexington Ave. at 60th St., 212/829-0651
  • Duane Reade (24-hour store), 1191 2nd Ave. at E. 63rd St., 212/355-5944
  • Duane Reade (24-hour store), 2025 Broadway at 69th St., 212/579-9955
  • Walgreen's (24-hour pharmacy), 1328 2nd Ave. at 70th St., 212/734-6076
  • CVS (24-hour pharmacy), 1396 2nd Ave. at 72nd St., 212/249-5699
  • Duane Reade (24-hour store), 1345 1st Ave. at 72nd St., 212/535-9816
  • Duane Reade (24-hour store and express kiosk), 253 W. 72nd St. at West End Ave., 212/580-0497
  • Duane Reade (24-hour pharmacy), 1279 3rd Ave./200 E. 74th St., 212/744-2668
  • Duane Reade (24-hour store), 1498 York Ave. at 79th St., 212/879-8990
  • Duane Reade (24-hour store), 380 Amsterdam Ave. at 79th St., 212/579-7246
  • Duane Reade (24-hour store), 401 E. 86th St. at 1st Ave., 917/492-8801
  • Duane Reade (24-hour store), 125 E. 86th St. at Lexington Ave., 212/996-5261
  • Duane Reade (24-hour store), 1231 Madison Ave. at 89th St., 212/360-6586
  • Duane Reade (24-hour store), 609 Columbus Ave. at 89th St., 212/724-4270
  • CVS (24-hour pharmacy) 1622 3rd Ave. at 91st St., 212/876-7016
  • Duane Reade (24-hour store), 1675 3rd Ave. at 93rd St., 212/348-7400
  • Duane Reade (24-hour pharmacy), 2522 Broadway at 94th St., 212/663-1580
  • Duane Reade (24-hour store), 2589 Broadway at 97th St., 212/864-5246
  • Duane Reade (24-hour store), 2864 Broadway at 111th St., 212/316-5113

Looking for more Manhattan essentials? Check out key About.com resources like Essential Manhattan Phone Numbers, How to Get a New York Driver's License, How to Get a Copy of Your NYC Birth Certificate, and more.

-- Updated by Elissa Garay