24-Hour Pharmacies in Manhattan

Where to Find a Round-the-Clock Drugstore in the Big Apple

Duane Reade pharmacy (at 4 Times Square plaza), New York, New York, January 1, 2013
Oliver Morris/Getty Images

Whether you need cough medicine for your little one or an emergency prescription refill, sometimes you just can't wait until 9 am. These 24-hour Manhattan pharmacies are open around the clock, several have full-time pharmacy services.

To make it easier to find the pharmacy near you, Manhattan's been divided into three parts: downtown, midtown, and uptown.

Downtown (below 23rd St.)

  • Rite-Aid (24-hour pharmacy), 408 Grand St. at Clinton St., 212/529-7115
  • Duane Reade (24-hour store), 125 3rd Ave. at 14th St., 212/529-7140
  • Walgreen's (24-hour pharmacy), 145 4th Ave., at 14th St., 212/677-0054
  • Duane Reade (24-hour store), 598 Broadway, between Houston and Prince, 212/343-2567
  • Duane Reade (24-hour store), 180 W. 20th St. at 7th Ave., 212/243-0129
  • CVS (24-hour pharmacy), 342 E. 23rd St. at 2nd Ave. at 2nd Ave., 212/505-1555

Midtown (23rd to 60th sts.)

  • Duane Reade (24-hour store), 401 Park Ave. S. at 28th St., 212/213-9730
  • Duane Reade (24-hour store), 350 5th Ave. at 34th St., 212/279-0208
  • Duane Reade (24-hour store), 460 8th Ave. at 34th St., 212/244-4026
  • Duane Reade (24-hour pharmacy), 155 E. 34th St. at 3rd Ave., 212/683-3042
  • Duane Reade (24-hour store), 852 2nd Ave., btwn 45th & 46th sts., 212/983-1810
  • Duane Reade (24-hour store), 485 Lexington Ave. at 47th St., 212/682-5338
  • CVS (24-hour pharmacy), 630 Lexington Ave. at 53rd St., 917/369-8688
  • Duane Reade (24-hour store), 900 8th Ave. at 53rd St., 212/582-3463
  • Duane Reade (24-hour store), 866 3rd Ave. at 53rd St., 212/759-9412
  • Duane Reade (24-hour pharmacy), 949 3rd Ave. at 57th St., 212/223-1765
  • Duane Reade (24-hour store), 100 W. 57th St. at 6th Ave., 212/956-0464
  • Duane Reade (24-hour store), 4 Columbus Circle at 58th St., 212/265-2302
  • CVS (24-hour pharmacy), 400 W. 59th St. at Columbus Ave., 212/245-0617

Uptown (above 60th St.)

  • Duane Reade (24-hour store and express kiosk), 773 Lexington Ave. at 60th St., 212/829-0651
  • Duane Reade (24-hour store), 1191 2nd Ave. at E. 63rd St., 212/355-5944
  • Duane Reade (24-hour store), 2025 Broadway at 69th St., 212/579-9955
  • Walgreen's (24-hour pharmacy), 1328 2nd Ave. at 70th St., 212/734-6076
  • CVS (24-hour pharmacy), 1396 2nd Ave. at 72nd St., 212/249-5699
  • Duane Reade (24-hour store), 1345 1st Ave. at 72nd St., 212/535-9816
  • Duane Reade (24-hour pharmacy), 2069 Broadway at 72nd St., 212/799-1067
  • Duane Reade (24-hour store ), 1279 3rd Ave./200 E. 74th St., 212/744-2668
  • Duane Reade (24-hour store), 1498 York Ave. at 79th St., 212/879-8990
  • Duane Reade (24-hour store), 380 Amsterdam Ave. at 79th St., 212/579-7246
  • Duane Reade (24-hour store), 401 E. 86th St. at 1st Ave., 917/492-8801
  • Duane Reade (24-hour store), 1231 Madison Ave. at 89th St., 212/360-6586
  • Duane Reade (24-hour store), 609 Columbus Ave. at 89th St., 212/724-4270
  • CVS (24-hour pharmacy), 1622 3rd Ave. at 91st St., 212/876-7016
  • Duane Reade (24-hour store), 1675 3rd Ave. at 93rd St., 212/348-7400
  • Duane Reade (24-hour store), 2522 Broadway at 94th St., 212/663-1580
  • Duane Reade (24-hour store), 2589 Broadway at 97th St., 212/864-5246
  • Duane Reade (24-hour store), 775 Columbus at 98th St., 212/280-3085
  • Duane Reade (24-hour pharmacy), 2864 Broadway at 111th St., 212/316-5113